logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name hsa-miR-152-3p
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line vitreous humour, blood
Methods microarray, qPCR
Expression pattern down-regulated
Functional description We identified a disease-associated increase in miR-146a and a decrease in miR-106b and miR-152 in the vitreous humour which was reproducible in plasma. Using the AMD Gene Consortium (AGC) we mapped a NV AMD-associated SNP (rs1063320) in a binding site for miR-152-3p in the HLA-G gene.
PubMed ID 27015561
Year 2016
Title MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.